VS 2005 - The breakpoint will not currently be hit. No symbols loaded for this document.

Today something strange happen while just coding in ASP.NET with VS.NET 2005. Everything was just working fine, suddenly I got the error message :

" VS 2005 - The breakpoint will not currently be hit. No symbols loaded for this document. "

I was not able to debug the code in .cs files. I tried to find out the solution on the net with searching for " VS 2005 - The breakpoint will not currently be hit. No symbols loaded for this document. " in search engine. But no help. But I was sure here is some problem with the build process. Finally one thing I found one thing that this stores the some files at
"C:\Documents and Settings\UserId or Name\Local Settings\Application Data".

I deleted all the files in folder "Application Data"(exception few which I was not able to delete).
Then this was the step I must have performed in step 1. Yes this was all done and I was able to debug my application.